Mathematics > Analysis of PDEs
[Submitted on 24 Apr 2018]
Title:Estimating the division rate and kernel in the fragmentation equation
View PDFAbstract:We consider the fragmentation equation $\dfrac{\partial}{\partial t}f (t, x) = --B(x)f (t, x) + \int\_{ y=x}^{ y=\infty} k(y, x)B(y)f (t, y)dy,$ and address the question of estimating the fragmentation parameters-i.e. the division rate $B(x)$ and the fragmentation kernel $k(y, x)$-from measurements of the size distribution $f (t, $\times$)$ at various times. This is a natural question for any application where the sizes of the particles are measured experimentally whereas the fragmentation rates are unknown, see for instance (Xue, Radford, Biophys. Journal, 2013) for amyloid fibril breakage. Under the assumption of a polynomial division rate $B(x) = \alpha x^{\gamma}$ and a self-similar fragmentation kernel $k(y, x) = \frac{1}{y} k\_0 (x/ y)$, we use the asymptotic behaviour proved in (Escobedo, Mischler, Rodriguez-Ricard, Ann. IHP, 2004) to obtain uniqueness of the triplet $(\alpha, \gamma, k \_0)$ and a representation formula for $k\_0$. To invert this formula, one of the delicate points is to prove that the Mellin transform of the asymptotic profile never vanishes, what we do through the use of the Cauchy integral.
Submission history
From: Marie Doumic [view email] [via CCSD proxy][v1] Tue, 24 Apr 2018 10:34:52 UTC (68 KB)
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